Article
p53 exon 5 mutations in two cases of leukemic mantle cell lymphoma.
Cancer genetics and cytogenetics - 1 Feb 1996
Gandini D, Moretti S, Latorraca A, De Angeli C, Lanza F, Cuneo A, Castoldi G, del Senno L
Abstract excerpt
Although p53 mutations have been described frequently in high-grade B-cell non-Hodgkin's lymphoma (NHL), they have only been reported occasionally in low-grade NHL. We therefore describe clincobiologic and molecular genetic findings in two patients with p53 mutations and leukemic mantle cell lymphoma featuring an unusually aggressive course. Circulating malignant cells showed irregularity of nuclear outline with...
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