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Article

Heterogeneity of mesothelioma cell lines as defined by altered genomic structure and expression of the NF2 gene.

International journal of cancer - 12 Aug 1998

Deguen B, Goutebroze L, Giovannini M, Boisson C, van der Neut R, Jaurand M C, Thomas G

Abstract excerpt

Germ-line mutations in the neurofibromatosis 2 (NF2) gene cause a susceptibility to the development of schwannoma and meningioma, 2 mostly benign tumors of neural crest origin. Bi-allelic inactivation of this gene has been observed in sporadic schwannomas and meningiomas. The NF2 gene may also be somatically inactivated in human malignant mesotheliomas (HMMs). Surprisingly, patients with an NF2 germ-line mutation...

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Identifiers

PMID: 9679758
DOI: 10.1002/(sici)1097-0215(19980812)77:4<554::aid-ijc14>3.0.co;2-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Heterogeneity of mesothelioma cell lines as defined by altered genomic structure and expression of the NF2 gene.PMID 9679758Read ↗

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