Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular Analysis of a Patient With Neurofibromatosis 2 (NF2) and Peritoneal Malignant Mesothelioma

20 Sept 2019

Abstract excerpt

Neurofibromatosis type 2 (NF2), an inherited disorder associated with multiple inherited schwannomas, meningiomas and ependymomas is caused by an autosomal dominant, likely loss of function germline mutation of the NF2 gene. Interestingly, biallelic NF2 gene inactivation is one of the most common mutations associated with the development of malignant mesothelioma (MM), a highly fatal malignancy that arises in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neurofibromatosis and Schwannoma Cases
Share to Occupational and environmental lung diseases
Share to Soft tissue tumor case studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31567203
DOI: 10.1097/pas.0000000000001359

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular Analysis of a Patient With Neurofibromatosis 2 (NF2) and Peritoneal Malignant MesotheliomaPMID 31567203Read ↗

Neurofibromatosis type 2.Semantic proximity Read ↗

High frequency of inactivating mutations in the neurofibromatosis type 2 gene (NF2) in primary malignant mesotheliomas.Semantic proximity Read ↗

BAP1, a tumor suppressor gene driving malignant mesotheliomaSemantic proximity Read ↗

Neuropathology and Molecular Genetics of Neurofibromatosis 2 and Related TumorsSemantic proximity Read ↗

Meningiomas in Patients With Malignant Pleural Mesothelioma Harboring Germline BAP1 Mutations.Semantic proximity Read ↗

New strategies in pleural mesothelioma: BAP1 and NF2 as novel targets for therapeutic development and risk assessment.Semantic proximity Read ↗

Inherited genetic syndromes and meningiomas.Semantic proximity Read ↗

Frequent mutations of NF2 and allelic loss from chromosome band 22q12 in malignant mesothelioma: evidence for a two-hit mechanism of NF2 inactivation.Semantic proximity Read ↗

Germline SMARCB1 mutation and somatic NF2 mutations in familial multiple meningiomas.Semantic proximity Read ↗

Germline BAP1 Mutation in a Family With Multi-Generational Meningioma With Rhabdoid Features: A Case Series and Literature ReviewSemantic proximity Read ↗

Neurofibromatosis Type 2 (NF2): Molecular Insights and Therapeutic AvenuesSemantic proximity Read ↗

Predominant occurrence of somatic mutations of the NF2 gene in meningiomas and schwannomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.