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Glutathione S-transferase: genetics and role in toxicology.

Toxicology letters - 15 Mar 2000

Strange R C, Jones P W, Fryer A A

Abstract excerpt

The glutathione S-transferases (GST) are a supergene family of dimeric, enzymes that catalyse the conjugation of glutathione (GSH) to a variety of electrophiles including arene oxides, unsaturated carbonyls, organic halides and other substrates. Their importance is suggested by the finding that GST enzymes are expressed in probably all life forms. In humans, polymorphism in GST genes has been associated with...

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Identifiers

PMID: 10720752
DOI: 10.1016/s0378-4274(99)00230-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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