Glutathione S-transferase: genetics and role in toxicology.

doi:10.1016/s0378-4274(99)00230-1

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Glutathione S-transferase: genetics and role in toxicology.

Toxicology letters - 15 Mar 2000

Strange R C, Jones P W, Fryer A A

Abstract excerpt

The glutathione S-transferases (GST) are a supergene family of dimeric, enzymes that catalyse the conjugation of glutathione (GSH) to a variety of electrophiles including arene oxides, unsaturated carbonyls, organic halides and other substrates. Their importance is suggested by the finding that GST enzymes are expressed in probably all life forms. In humans, polymorphism in GST genes has been associated with...

Topics

Carcinoma, Basal Cell
Female
Genetic Predisposition to Disease
Glutathione Transferase
Humans
Ovarian Neoplasms
Polymorphism, Genetic
Skin Neoplasms
Toxicology

Source

Open in PubMed

Identifiers

PMID: 10720752
DOI: 10.1016/s0378-4274(99)00230-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics