Article
GSTP1 and cancer: Expression, methylation, polymorphisms and signaling (Review).
International journal of oncology - 1 Apr 2020
Cui Jian, Li Guoqing, Yin Jie, Li Linwei, Tan Yue, Wei Haoran, Liu Bang, Deng Lihong, Tang Jialu, Chen Yonglin, Yi Lan
Abstract excerpt
Glutathione S‑transferase Pi (GSTP1) is an isozyme encoded by the GST pi gene that plays an important regulatory role in detoxification, anti‑oxidative damage, and the occurrence of various diseases. The aim of the present study was to review the association between the expression of GSTP1 and the development and treatment of various cancers, and discuss GSTP1 methylation in several malignant tumors, such as...
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