Article
Pleiotropic functions of glutathione S-transferase P.
Advances in cancer research - 1 Jan 2014
Zhang Jie, Grek Christina, Ye Zhi-Wei, Manevich Yefim, Tew Kenneth D, Townsend Danyelle M
Abstract excerpt
Glutathione S-transferase P (GSTP) is one member of the GST superfamily that is prevalently expressed in mammals. Known to possess catalytic activity through deprotonating glutathione allowing formation of thioether bonds with electrophilic substrates, more recent discoveries have broadened our understanding of the biological roles of this protein. In addition to catalytic detoxification, other properties so far...
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