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Article

Requirement for the vasa RNA helicase in gurken mRNA localization.

Developmental biology - 1 Jul 1998

Tinker R, Silver D, Montell D J

Abstract excerpt

Localization of specific mRNAs to distinct sites within the Drosophila oocyte is an early and key step in establishing the anterior-posterior and dorsal-ventral axes. We describe a new function for the RNA helicase encoded by the "posterior" group gene vasa (vas) in control of localization of the mRNA encoded by the "dorsal-ventral" patterning gene gurken (grk). Two new ethyl methane sulfonate-induced, female...

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Identifiers

PMID: 9676188
DOI: 10.1006/dbio.1998.8941

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Requirement for the vasa RNA helicase in gurken mRNA localization.PMID 9676188Read ↗

Oocyte polarity depends on regulation of gurken by Vasa.Semantic proximity Read ↗

<i>vasa</i> is required for GURKEN accumulation in the oocyte, and is involved in oocyte differentiation and germline cyst developmentSemantic proximity Read ↗

VASA localization requires the SPRY-domain and SOCS-box containing protein, GUSTAVUS.Semantic proximity Read ↗

Drosophila Hephaestus/polypyrimidine tract binding protein is required for dorso-ventral patterning and regulation of signalling between the germline and soma.Semantic proximity Read ↗

The angle of the dorsoventral axis with respect to the anteroposterior axis in the Drosophila embryo is controlled by the distribution of gurken mRNA in the oocyte.Semantic proximity Read ↗

maelstrom is required for an early step in the establishment of Drosophila oocyte polarity: posterior localization of grk mRNA.Semantic proximity Read ↗

Initial organization of the Drosophila dorsoventral axis depends on an RNA-binding protein encoded by the squid gene.Semantic proximity Read ↗

The RNA-binding protein Squid is required for the establishment of anteroposterior polarity in the Drosophila oocyte.Semantic proximity Read ↗

A genetic screen based on in vivo RNA imaging reveals centrosome-independent mechanisms for localizing gurken transcripts in Drosophila.Semantic proximity Read ↗

The Drosophila dorsoventral patterning gene gurken produces a dorsally localized RNA and encodes a TGF alpha-like protein.Semantic proximity Read ↗

The role of oocyte transcription, the 5'UTR, and translation repression and derepression in Drosophila gurken mRNA and protein localization.Semantic proximity Read ↗

Evidence for a transport-trap mode of Drosophila melanogaster gurken mRNA localization.Semantic proximity Read ↗

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