Article
maelstrom is required for an early step in the establishment of Drosophila oocyte polarity: posterior localization of grk mRNA.
Development (Cambridge, England) - 1 Nov 1997
Clegg N J, Frost D M, Larkin M K, Subrahmanyan L, Bryant Z, Ruohola-Baker H
Abstract excerpt
We describe a mutant, maelstrom, that disrupts a previously unobserved step in mRNA localization within the early oocyte, distinct from nurse-cell-to-oocyte RNA transport. Mutations in maelstrom disturb the localization of mRNAs for Gurken (a ligand for the Drosophila Egf receptor), Oskar and Bic...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Polarity
- Cloning, Molecular
- DNA
- Drosophila Proteins
- Drosophila melanogaster
- ErbB Receptors
- Female
- Gene Expression Regulation, Developmental
- Genes, Insect
- Insect Proteins
- Microtubules
- Molecular Sequence Data
- Mutation
- Oocytes
- RNA, Messenger