Article
maelstrom is required for an early step in the establishment of Drosophila oocyte polarity: posterior localization of grk mRNA.
Development (Cambridge, England) - 1 Nov 1997
Clegg N J, Frost D M, Larkin M K, Subrahmanyan L, Bryant Z, Ruohola-Baker H
Abstract excerpt
We describe a mutant, maelstrom, that disrupts a previously unobserved step in mRNA localization within the early oocyte, distinct from nurse-cell-to-oocyte RNA transport. Mutations in maelstrom disturb the localization of mRNAs for Gurken (a ligand for the Drosophila Egf receptor), Oskar and Bicoid at the posterior of the developing (stage 3-6) oocyte. maelstrom mutants display phenotypes detected in gurken...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
