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Article

The role of oocyte transcription, the 5'UTR, and translation repression and derepression in Drosophila gurken mRNA and protein localization.

Molecular cell - 1 Jan 1999

Saunders C, Cohen R S

Abstract excerpt

The establishment of the major body axes of the Drosophila egg and future embryo requires strict regulation of gurken mRNA and protein localization. Here, we show that grk mRNA and protein localization is dependent on synthesis of grk transcripts in the oocyte nucleus and on RNA localization elements in the 5' portion of the transcript. We also show that gurken mRNA and protein localization is dependent on...

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PMID: 10024878
DOI: 10.1016/s1097-2765(00)80173-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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The role of oocyte transcription, the 5'UTR, and translation repression and derepression in Drosophila gurken mRNA and protein localization.PMID 10024878Read ↗

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The dynamics of fluorescently labeled endogenous gurken mRNA in Drosophila.Semantic proximity Read ↗

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A genetic screen based on in vivo RNA imaging reveals centrosome-independent mechanisms for localizing gurken transcripts in Drosophila.Semantic proximity Read ↗

maelstrom is required for an early step in the establishment of Drosophila oocyte polarity: posterior localization of grk mRNA.Semantic proximity Read ↗

Squid, Cup, and PABP55B function together to regulate gurken translation in Drosophila.Semantic proximity Read ↗

Post-transcriptional regulation of gurken by encore is required for axis determination in Drosophila.Semantic proximity Read ↗

Specific isoforms of squid, a Drosophila hnRNP, perform distinct roles in Gurken localization during oogenesis.Semantic proximity Read ↗

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Evidence for a highly selective RNA transport system and its role in establishing the dorsoventral axis of the Drosophila egg.Semantic proximity Read ↗

Encore is a member of a novel family of proteins and affects multiple processes in Drosophila oogenesis.Semantic proximity Read ↗

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