Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

VASA localization requires the SPRY-domain and SOCS-box containing protein, GUSTAVUS.

Developmental cell - 1 Dec 2002

Styhler Sylvia, Nakamura Akira, Lasko Paul

Abstract excerpt

VASA (VAS), a key protein in establishing the specialized translational activity of the Drosophila pole plasm, accumulates at the posterior pole of the developing oocyte. We identified a gene, gustavus (gus), that encodes a protein that interacts with VAS. A gus mutation blocks posterior localization of VAS, as does deletion of a segment of VAS containing the GUS binding site. Like VAS, GUS is present in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Compartmentation
Share to Cell Polarity
Share to DEAD-box RNA Helicases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Oocytes

Share to Oogenesis

Share to RNA Helicases

Source

Identifiers

PMID: 12479811
DOI: 10.1016/s1534-5807(02)00361-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

VASA localization requires the SPRY-domain and SOCS-box containing protein, GUSTAVUS.PMID 12479811Read ↗

<i>vasa</i> is required for GURKEN accumulation in the oocyte, and is involved in oocyte differentiation and germline cyst developmentSemantic proximity Read ↗

Oocyte polarity depends on regulation of gurken by Vasa.Semantic proximity Read ↗

Localization of vasa, a component of Drosophila polar granules, in maternal-effect mutants that alter embryonic anteroposterior polarity.Semantic proximity Read ↗

pipsqueak, an early acting member of the posterior group of genes, affects vasa level and germ cell-somatic cell interaction in the developing egg chamber.Semantic proximity Read ↗

A late phase of germ plasm accumulation during Drosophila oogenesis requires lost and rumpelstiltskin.Semantic proximity Read ↗

Requirement for the vasa RNA helicase in gurken mRNA localization.Semantic proximity Read ↗

Oskar organizes the germ plasm and directs localization of the posterior determinant nanos.Semantic proximity Read ↗

Drosophila valois encodes a divergent WD protein that is required for Vasa localization and Oskar protein accumulation.Semantic proximity Read ↗

Multiple RNA regulatory elements mediate distinct steps in localization of oskar mRNA.Semantic proximity Read ↗

The endocytic pathway acts downstream of Oskar in Drosophila germ plasm assembly.Semantic proximity Read ↗

oskar mRNA is localized to the posterior pole of the Drosophila oocyte.Semantic proximity Read ↗

Squid is required for efficient posterior localization of oskar mRNA during Drosophila oogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.