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Article

<i>vasa</i> is required for GURKEN accumulation in the oocyte, and is involved in oocyte differentiation and germline cyst development

1 May 1998

Abstract excerpt

The Drosophila gene vasa is required for pole plasm assembly and function, and also for completion of oogenesis. To investigate the role of vasa in oocyte development, we generated a new null mutation of vasa, which deletes the entire coding region. Analysis of vasa-null ovaries revealed that the gene is involved in the growth of germline cysts. In vasa-null ovaries, germaria are atrophied, and contain far fewer...

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Identifiers

PMID: 9521895
DOI: 10.1242/dev.125.9.1569

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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<i>vasa</i> is required for GURKEN accumulation in the oocyte, and is involved in oocyte differentiation and germline cyst developmentPMID 9521895Read ↗

Oocyte polarity depends on regulation of gurken by Vasa.Semantic proximity Read ↗

A late phase of germ plasm accumulation during Drosophila oogenesis requires lost and rumpelstiltskin.Semantic proximity Read ↗

VASA localization requires the SPRY-domain and SOCS-box containing protein, GUSTAVUS.Semantic proximity Read ↗

Zebrafish vasa is required for germ-cell differentiation and maintenance.Semantic proximity Read ↗

Requirement for the vasa RNA helicase in gurken mRNA localization.Semantic proximity Read ↗

Maternal Nanos and Pumilio regulate zygotic vasa expression autonomously in the germ-line progenitors of Drosophila melanogaster embryos.Semantic proximity Read ↗

Oskar organizes the germ plasm and directs localization of the posterior determinant nanos.Semantic proximity Read ↗

maelstrom is required for an early step in the establishment of Drosophila oocyte polarity: posterior localization of grk mRNA.Semantic proximity Read ↗

Localization of vasa, a component of Drosophila polar granules, in maternal-effect mutants that alter embryonic anteroposterior polarity.Semantic proximity Read ↗

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