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Article

A chicken c-Rel-estrogen receptor chimeric protein shows conditional nuclear localization, DNA binding, transformation and transcriptional activation.

Oncogene - 18 Jun 1998

Zurovec M, Petrenko O, Roll R, Enrietto P J

Abstract excerpt

In this report, we characterize the biological and biochemical properties of a conditional protein containing chicken c-Rel fused to the hormone-binding domain of the human estrogen receptor. This chimeric c-RelER protein causes estrogen-dependent, but otherwise c-Rel-specific, transformation of avian fibroblasts in vitro. Our results demonstrate that c-RelER heterodimerizes with wild-type c-Rel and forms...

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Identifiers

PMID: 9671392
DOI: 10.1038/sj.onc.1201860

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A chicken c-Rel-estrogen receptor chimeric protein shows conditional nuclear localization, DNA binding, transformation and transcriptional activation.PMID 9671392Read ↗

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Efficient transformation of chicken embryo fibroblasts by c-Jun requires structural modification in coding and noncoding sequences.Semantic proximity Read ↗

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