Article
A conditional mutant of vRel containing sequences from the human estrogen receptor.
Virology - 1 Mar 1993
Capobianco A J, Gilmore T D
Abstract excerpt
The mechanism by which the v-rel oncogene of the avian Rev-T retrovirus transforms chicken spleen cells is not known. We have created v-rel mutants that show conditional properties by fusing sequences encoding the ligand-binding domain of the human estrogen receptor (ER) in-frame at the 3' end of...
Topics
- Animals
- Cells, Cultured
- Chick Embryo
- Chickens
- DNA, Viral
- DNA-Binding Proteins
- Humans
- Mutation
- Oncogene Proteins v-rel
- Receptors, Estrogen
- Recombinant Fusion Proteins
- Repressor Proteins
- Retroviridae Proteins, Oncogenic
- Transformation, Genetic