High colony forming capacity of primary cultured hepatocytes as a dominant trait in hepatocarcinogenesis-susceptible and resistant mouse strains.

doi:10.1093/carcin/19.6.1103

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Article

High colony forming capacity of primary cultured hepatocytes as a dominant trait in hepatocarcinogenesis-susceptible and resistant mouse strains.

Carcinogenesis - 1 Jun 1998

Yoshie M, Nishimori H, Lee G H, Ogawa K

Abstract excerpt

When hepatocytes isolated from mouse liver are cultivated in vitro, a small fraction of cells can survive, forming colonies, while most cells die within a few weeks. We compared the colony forming capacity of hepatocytes in three mouse strains; two strains susceptible for hepatocarcinogenesis, C3...

Topics

Animals
Apoptosis
Cell Division
Cells, Cultured
Genetic Predisposition to Disease
Liver
Liver Neoplasms, Experimental
Mice
Species Specificity

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