Article
Heterogeneity of growth potential of adult rat hepatocytes in vitro.
Hepatology (Baltimore, Md.) - 1 Jan 2000
Tateno C, Takai-Kajihara K, Yamasaki C, Sato H, Yoshizato K
Abstract excerpt
Nearly pure populations of small hepatocytes (SHs), parenchymal hepatocytes (PHs), and nonparenchymal cells (NPCs) were prepared from the adult rat, and cocultures of hepatocytes and NPCs were reconstituted from them first to obtain the direct evidence that NPCs promote the growth of hepatocytes and second to compare the growth potential between SHs and PHs. SHs and PHs underwent multiple divisions when...
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