Article
Size-dependent in vivo growth potential of adult rat hepatocytes.
The American journal of pathology - 1 Jan 2001
Katayama S, Tateno C, Asahara T, Yoshizato K
Abstract excerpt
The present study was performed to determine whether hepatocytes show a size-dependent growth in vivo using as a growth assay system, a retrorsine/partial hepatectomy model of dipeptidyl dipeptidase IV-deficient (DPPIV(-)) mutant Fischer rats. Nearly pure populations of small hepatocytes (SHs) and parenchymal hepatocytes (PHs) were prepared from DPPIV(+) rats. The same number of these SHs and PHs was transplanted...
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