Growth and differentiation in culture of clonogenic hepatocytes that express both phenotypes of hepatocytes and biliary epithelial cells.

Article

Growth and differentiation in culture of clonogenic hepatocytes that express both phenotypes of hepatocytes and biliary epithelial cells.

The American journal of pathology - 1 Nov 1996

Tateno C, Yoshizato K

Abstract excerpt

A cell fraction containing small hepatocytes and nonparenchymal cells was isolated from the adult rat liver and was cultured in the presence of vitamin C. epidermal growth factor, nicotinamide, and dimethylsulfoxide. All of the small hepatocytes that had attached to a dish expressed hepatocytic p...

Topics

Animals
Bile Ducts
Cell Differentiation
Cell Division
Cells, Cultured
Clone Cells
Epithelial Cells
Epithelium
Liver
Male
Mitotic Index
Phenotype
Rats
Rats, Inbred F344

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