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Growth potential and differentiation capacity of adult rat hepatocytes in vitro.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society - 1 Jan 2000

Tateno C, Yoshizato K

Abstract excerpt

We have previously reported a medium that supports the continuous growth of hepatocytes without their losing replicative potential and differentiation capacity for an extended period. The medium contains four key substances in addition to fetal bovine serum, that is, epidermal growth factor, nicotinamide, ascorbic acid 2-phosphate, and dimethyl sulfoxide. When a nonparenchymal cell fraction containing small...

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PMID: 10231504
DOI: 10.1046/j.1524-475x.1999.00036.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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