Article
Bone marrow transplantation in mice leads to a minor population of hepatocytes that can be selectively amplified in vivo
1 Apr 2002
Abstract excerpt
Cell-based therapy may some day be a therapeutic alternative to liver transplantation. Recent observations indicating that hematopoietic stem cells can differentiate into hepatocytes have opened new therapeutic prospects. However, the clinical relevance of this phenomenon is unknown. We have previously developed a strategy based on the protective effect of Bcl-2 against Fas-mediated apoptosis to selectively...
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