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Article

Man-made cell-like compartments for molecular evolution.

Nature biotechnology - 1 Jul 1998

Tawfik D S, Griffiths A D

Abstract excerpt

Cellular compartmentalization is vital for the evolution of all living organisms. Cells keep together the genes, the RNAs and proteins that they encode, and the products of their activities, thus linking genotype to phenotype. We have reproduced this linkage in the test tube by transcribing and translating single genes in the aqueous compartments of water-in-oil emulsions. These compartments, with volumes close...

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PMID: 9661199
DOI: 10.1038/nbt0798-652

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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