Absence of Gcn5 HAT activity defines a novel state in the opening of chromatin at the PHO5 promoter in yeast.

doi:10.1016/s1097-2765(00)80050-7

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Article

Absence of Gcn5 HAT activity defines a novel state in the opening of chromatin at the PHO5 promoter in yeast.

Molecular cell - 1 Mar 1998

Gregory P D, Schmid A, Zavari M, Lui L, Berger S L, Hörz W

Abstract excerpt

Histone acetyltransferase (HAT) activity has been demonstrated for several transcriptional activators, formally connecting chromatin modification with gene regulation. However, no effect on chromatin has been demonstrated. We have investigated the role of the HAT Gcn5 at the nucleosomally regulat...

Topics

Acetyltransferases
Chromatin
DNA-Binding Proteins
Fungal Proteins
Gene Deletion
Gene Expression Regulation, Fungal
Histone Acetyltransferases
Membrane Transport Proteins
Mutagenesis
Phenotype
Phosphate Transport Proteins
Promoter Regions, Genetic
Protein Kinases
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Transcription, Genetic

Source

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Identifiers

PMID: 9660934
DOI: 10.1016/s1097-2765(00)80050-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9660934-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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