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Article

Role of trans-activating proteins in the generation of active chromatin at the PHO5 promoter in S. cerevisiae.

The EMBO journal - 1 Aug 1990

Fascher K D, Schmitz J, Hörz W

Abstract excerpt

Induction of the PHO5 gene in Saccharomyces cerevisiae by phosphate starvation was previously shown to be accompanied by the removal of four positioned nucleosomes from the promoter. We have now investigated the role of two trans-activating proteins, encoded by PHO2 and PHO4, which bind to the PHO5 promoter. Both proteins are absolutely required for the chromatin transition to occur as shown by analysis of null...

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Identifiers

PMID: 2196175
DOI: 10.1002/j.1460-2075.1990.tb07432.x
PMCID: PMC552282

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Role of trans-activating proteins in the generation of active chromatin at the PHO5 promoter in S. cerevisiae.PMID 2196175Read ↗

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