Regulation of PHO4 nuclear localization by the PHO80-PHO85 cyclin-CDK complex.

doi:10.1126/science.271.5246.209

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Article

Regulation of PHO4 nuclear localization by the PHO80-PHO85 cyclin-CDK complex.

Science (New York, N.Y.) - 12 Jan 1996

O'Neill E M, Kaffman A, Jolly E R, O'Shea E K

Abstract excerpt

PHO4, a transcription factor required for induction of the PHO5 gene in response to phosphate starvation, is phosphorylated by the PHO80-PHO85 cyclin-CDK (cyclin-dependent kinase) complex when yeast are grown in phosphate-rich medium. PHO4 was shown to be concentrated in the nucleus when yeast we...

Topics

Amino Acid Sequence
Cell Nucleus
Culture Media
Cyclin-Dependent Kinases
Cyclins
Cytoplasm
DNA-Binding Proteins
Dipeptides
Fungal Proteins
Gene Expression Regulation, Fungal
Membrane Transport Proteins
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Phosphate Transport Proteins

Phosphates

Phosphorylation

Repressor Proteins

Saccharomyces cerevisiae

Source

Open in PubMed

Identifiers

PMID: 8539622
DOI: 10.1126/science.271.5246.209

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8539622-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Regulation of PHO4 nuclear localization by the PHO80-PHO85 cyclin-CDK complex.PMID 8539622Read ↗

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