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Article

Quantitative analysis of the transcription control mechanism.

Molecular systems biology - 19 Nov 2010

Mao Changhui, Brown Christopher R, Falkovskaia Elena, Dong Shawfeng, Hrabeta-Robinson Eva, Wenger Lauren, Boeger Hinrich

Abstract excerpt

Gene transcription requires a sequence of promoter state transitions, including chromatin remodeling, assembly of the transcription machinery, and clearance of the promoter by RNA polymerase. The rate-limiting steps in this sequence are regulated by transcriptional activators that bind at specific promoter elements. As the transition kinetics of individual promoters cannot be observed, the identity of the...

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Identifiers

PMID: 21081924
DOI: 10.1038/msb.2010.83
PMCID: PMC3010110

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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