Article
Cell cycle-specified fluctuation of nucleosome occupancy at gene promoters.
PLoS genetics - 22 Sept 2006
Hogan Gregory J, Lee Cheol-Koo, Lieb Jason D
Abstract excerpt
The packaging of DNA into nucleosomes influences the accessibility of underlying regulatory information. Nucleosome occupancy and positioning are best characterized in the budding yeast Saccharomyces cerevisiae, albeit in asynchronous cell populations or on individual promoters such as PHO5 and GAL1-10. Using FAIRE (formaldehyde-assisted isolation of regulatory elements) and whole-genome microarrays, we examined...
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