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Article

Morphology of sporadic colorectal cancer with DNA replication errors

1 May 1998

Abstract excerpt

BACKGROUND: Up to 15% of colorectal cancers are characterised by DNA microsatellite instability (MIN), shown by the presence of DNA replication errors (RERs). AIMS: To identify pathological features that are discriminating for colorectal cancer (CRC) showing extensive MIN. SUBJECTS: A prospective series of 303 patients with CRC and no family history of either familial adenomatous polyposis or hereditary...

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PMID: 9659163
DOI: 10.1136/gut.42.5.673

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