Article
Histopathological identification of colon cancer with microsatellite instability.
The American journal of pathology - 1 Feb 2001
Alexander J, Watanabe T, Wu T T, Rashid A, Li S, Hamilton S R
Abstract excerpt
Cancer with high levels of microsatellite instability (MSI-H) is the hallmark of hereditary nonpolyposis colorectal cancer syndrome, and MSI-H occurs in approximately 15% of sporadic colorectal carcinomas that have improved prognosis. We examined the utility of histopathology for the identification of MSI-H cancers by evaluating the features of 323 sporadic carcinomas using specified criteria and comparing the...
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