Sensitivity to cisplatin and platinum-containing compounds of Schizosaccharomyces pombe rad mutants.

doi:10.1124/mol.54.1.213

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Article

Sensitivity to cisplatin and platinum-containing compounds of Schizosaccharomyces pombe rad mutants.

Molecular pharmacology - 1 Jul 1998

Perego P, Zunino F, Carenini N, Giuliani F, Spinelli S, Howell S B

Abstract excerpt

The role of genes that affect response to radiation in determining sensitivity to platinum-containing compounds was studied using a panel of 23 strains of the yeast Schizosaccharomyces pombe. The radiation-hypersensitive mutants all had the same genetic background and most of them contained mutat...

Topics

Cell Cycle
Cisplatin
DNA Repair
DNA, Fungal
Microbial Sensitivity Tests
Mutation
Platinum Compounds
Radiation-Sensitizing Agents
Schizosaccharomyces

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