Article
DNA damage checkpoints are involved in postreplication repair.
Genetics - 1 Dec 2006
Barbour Leslie, Ball Lindsay G, Zhang Ke, Xiao Wei
Abstract excerpt
Saccharomyces cerevisiae MMS2 encodes a ubiquitin-conjugating enzyme variant, belongs to the error-free branch of the RAD6 postreplication repair (PRR) pathway, and is parallel to the REV3-mediated mutagenesis branch. A mutation in genes of either the MMS2 or the REV3 branch does not result in extreme sensitivity to DNA-damaging agents; however, deletion of both subpathways of PRR results in a synergistic...
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