DNA repair mutants defining G2 checkpoint pathways in Schizosaccharomyces pombe.

doi:10.1002/j.1460-2075.1992.tb05179.x

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Article

DNA repair mutants defining G2 checkpoint pathways in Schizosaccharomyces pombe.

The EMBO journal - 1 Apr 1992

al-Khodairy F, Carr A M

Abstract excerpt

We have tested mutants corresponding to 20 DNA repair genes of the fission yeast Schizosaccharomyces pombe for their ability to arrest in G2 after DNA damage. Of the mutants tested, four are profoundly defective in this damage dependent G2 arrest. In addition, these four mutants are highly sensit...

Topics

Cell Cycle
Crosses, Genetic
DNA Damage
DNA Repair
G2 Phase
Hydroxyurea
Kinetics
Mutation
Schizosaccharomyces
Time Factors

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