Article
Separation of phenotypes in mutant alleles of the Schizosaccharomyces pombe cell-cycle checkpoint gene rad1+.
Molecular biology of the cell - 1 Dec 1995
Kanter-Smoler G, Knudsen K E, Jimenez G, Sunnerhagen P, Subramani S
Abstract excerpt
The Schizosaccharomyces pombe rad1+ gene is involved in the G2 DNA damage cell-cycle checkpoint and in coupling mitosis to completed DNA replication. It is also required for viability when the cdc17 (DNA ligase) or wee1 proteins are inactivated. We have introduced mutations into the coding region...
Topics
- Alleles
- Base Sequence
- Cell Cycle
- DNA Damage
- DNA Primers
- DNA Replication
- DNA-Binding Proteins
- Dose-Response Relationship, Radiation
- Drug Resistance, Microbial
- Endonucleases
- Fungal Proteins
- Gamma Rays
- Genes, Fungal
- Genotype
- Hydroxyurea
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Phenotype