Article
Osteoblastic responses to TGF-beta during bone remodeling.
Molecular biology of the cell - 1 Jul 1998
Erlebacher A, Filvaroff E H, Ye J Q, Derynck R
Abstract excerpt
Bone remodeling depends on the spatial and temporal coupling of bone formation by osteoblasts and bone resorption by osteoclasts; however, the molecular basis of these inductive interactions is unknown. We have previously shown that osteoblastic overexpression of TGF-beta2 in transgenic mice dere...
Topics
- Alendronate
- Animals
- Bone Remodeling
- Bone Resorption
- Cell Count
- Cell Differentiation
- Femur
- Gene Expression Regulation
- Kinetics
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Minerals
- Osteoblasts
- Osteoclasts
- Osteocytes
- Periosteum
- Phenotype