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Article

Osteoblastic responses to TGF-beta during bone remodeling.

Molecular biology of the cell - 1 Jul 1998

Erlebacher A, Filvaroff E H, Ye J Q, Derynck R

Abstract excerpt

Bone remodeling depends on the spatial and temporal coupling of bone formation by osteoblasts and bone resorption by osteoclasts; however, the molecular basis of these inductive interactions is unknown. We have previously shown that osteoblastic overexpression of TGF-beta2 in transgenic mice deregulates bone remodeling and leads to an age-dependent loss of bone mass that resembles high-turnover osteoporosis in...

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Identifiers

PMID: 9658179
DOI: 10.1091/mbc.9.7.1903
PMCID: PMC25433

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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