Article
Proficient deoxyribonucleic acid repair of methylation damage in hamster ERCC-gene mutants.
Mutation research - 1 Jun 1998
Nexø B A, Dybdahl M, Damgaard J, Olsen L S, Møller P, Wassermann K
Abstract excerpt
Three major pathways, nucleotide excision repair (NER), base excision repair (BER) and O6-methylguanine-DNA methyltransferase (MGMT), are responsible for the removal of most adducts to DNA and thus for the survival of cells influenced by deoxyribonucleic acid (DNA) adduct-forming chemicals. We ha...
Topics
- Animals
- CHO Cells
- Cricetinae
- DNA Adducts
- DNA Damage
- DNA Methylation
- DNA Repair
- DNA-Binding Proteins
- Endonucleases
- Female
- Mutation
- Proteins
