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Article

Proficient deoxyribonucleic acid repair of methylation damage in hamster ERCC-gene mutants.

Mutation research - 1 Jun 1998

Nexø B A, Dybdahl M, Damgaard J, Olsen L S, Møller P, Wassermann K

Abstract excerpt

Three major pathways, nucleotide excision repair (NER), base excision repair (BER) and O6-methylguanine-DNA methyltransferase (MGMT), are responsible for the removal of most adducts to DNA and thus for the survival of cells influenced by deoxyribonucleic acid (DNA) adduct-forming chemicals. We have evaluated host cell reactivation and cell survival of wild type Chinese hamster ovary cells and of mutants in the...

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Source

Identifiers

PMID: 9653452
DOI: 10.1016/s0921-8777(98)00011-1

Genes

MGMT
ERCC1
ERCC2
ERCC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Proficient deoxyribonucleic acid repair of methylation damage in hamster ERCC-gene mutants.PMID 9653452Read ↗

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