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Modulation of repair of ultraviolet damage in the host-cell reactivation assay by polymorphic XPC and XPD/ERCC2 genotypes.

Carcinogenesis - 1 Feb 2002

Qiao Yawei, Spitz Margaret R, Shen Hongbing, Guo Zhaozheng, Shete Sanjay, Hedayati Mohammad, Grossman Lawrence, Mohrenweiser Harvey, Wei Qingyi

Abstract excerpt

DNA repair capacity (DRC) plays an important role in genetic susceptibility to cancer. Polymorphisms of a number of DNA repair genes involved in several distinct pathways have been identified. However, their effects on repair function have not been well characterized. We demonstrated previously that DRC for removal of benzo[a]pyrene diol epoxide-induced DNA damage measured by a host-cell reactivation assay was...

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Source

Identifiers

PMID: 11872635
DOI: 10.1093/carcin/23.2.295

Genes

XPC
XRCC1
ERCC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Modulation of repair of ultraviolet damage in the host-cell reactivation assay by polymorphic XPC and XPD/ERCC2 genotypes.PMID 11872635Read ↗

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