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Article

Molecular characterization of a common fragile site ( <i>FRA7H</i> ) on human chromosome 7 by the cloning of a simian virus 40 integration site

7 Jul 1998

Abstract excerpt

Common fragile sites are chromosomal loci prone to breakage and rearrangement, hypothesized to provide targets for foreign DNA integration. We cloned a simian virus 40 integration site and showed by fluorescent in situ hybridization analysis that the integration event had occurred within a common aphidicolin-induced fragile site on human chromosome 7, FRA7H. A region of 161 kb spanning FRA7H was defined and...

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PMID: 9653154
DOI: 10.1073/pnas.95.14.8141

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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