Article
Investigation of genetic susceptibility to non-small cell lung cancer by fragile site expression.
Teratogenesis, carcinogenesis, and mutagenesis - 1 Jan 2002
Tunca Berrin, Cecener Gulsah, Gebitekin Cengiz, Egeli Unal, Ediz Bulent, Ercan Ilker
Abstract excerpt
Fragile sites are non-staining gaps and breaks in specific points of chromosomes that are inducible by various culture conditions. Previous studies have shown that various clastogenic agents increase expression of fragile sites. In this study, the expression of common fragile sites induced by aphidicolin was evaluated on prometaphase chromosomes obtained from peripheral blood lymphocytes. Chromosomal aberrations...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
