The expression of common fragile sites and genetic predisposition to squamous cell lung cancers.

doi:10.1016/s0165-4608(96)00215-4

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Article

The expression of common fragile sites and genetic predisposition to squamous cell lung cancers.

Cancer genetics and cytogenetics - 1 Jun 1997

Egeli U, Karadağ M, Tunca B, Ozyardímcí N

Abstract excerpt

The chromosomal aberration rates (including gaps and breaks) and expression frequency of fragile sites were determined in peripheral blood lymphocytes cultured with TC 199 medium from 8 patients with squamous cell lung cancer, 10 of their first-degree relatives, and 12 healthy control subjects. A...

Topics

Carcinoma, Squamous Cell
Chromosome Fragile Sites
Chromosome Fragility
Female
Genetic Predisposition to Disease
Humans
Lung Neoplasms
Male
Middle Aged
Pedigree

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