Article
Characterization of the human TESTIN gene localized in the FRA7G region at 7q31.2.
Genomics - 15 Aug 2000
Tatarelli C, Linnenbach A, Mimori K, Croce C M
Abstract excerpt
Cancer-associated chromosomal aberrations often involve regions containing fragile sites. FRA7G is a common aphidicolin-inducible fragile site at 7q31.2, showing loss of heterozygosity in human malignancies. To investigate the structure of FRA7G, we constructed a bacterial artificial chromosome contig spanning the region between marker D7S486 and Met H. Analysis of the FRA7G sequence allowed us to identify a gene...
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