Article
Mutations at coding mononucleotide repeats in gastric cancer with the microsatellite mutator phenotype.
Oncogene - 28 May 1998
Ottini L, Falchetti M, D'Amico C, Amorosi A, Saieva C, Masala G, Frati L, Cama A, Palli D, Mariani-Costantini R
Abstract excerpt
We analysed 50 gastric carcinomas (GCs) to verify whether mutations at coding repeats were associated with microsatellite instability (MSI). The tumors included: ten cases with no MSI, 14 cases with MSI = 1 locus, 13 cases with MSI = two loci and 13 cases with MSI > or = 3 loci. We investigated c...
Topics
- Aged
- BRCA2 Protein
- Cadherins
- DNA, Neoplasm
- DNA-Binding Proteins
- Female
- Humans
- Male
- Microsatellite Repeats
- Middle Aged
- Multidrug Resistance-Associated Proteins
- MutS Homolog 3 Protein
- Mutation
- Neoplasm Proteins
- Phenotype