Article
Assessment of the beneficial loci and prognostic implications of microsatellite instability in gastric carcinoma.
Molecular medicine reports - 1 Jan 2000
Kang Ji Un, Koo Sun Hoe
Abstract excerpt
Microsatellite instability (MSI) is a hyper-mutable phenotype caused by the loss of DNA mismatch repair activity, and plays a crucial role in gastric carcinogenesis. To clarify the role of genetic instability in relation to clinicopathological variables, and to identify predictive MSI markers that facilitate the early detection and improve the classification of gastric carcinomas (GCs), 13 microsatellite (MS)...
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