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Article

Evolution of instability at coding and non-coding repeat sequences in human MSI-H colorectal cancers.

Human molecular genetics - 1 Mar 2001

Duval A, Rolland S, Compoint A, Tubacher E, Iacopetta B, Thomas G, Hamelin R

Abstract excerpt

A number of human genes containing coding mononucleotide repeat sequences are particularly prone to mutations in tumors with defects in mismatch repair (MMR) genes (MSI-H cancers). In a large series of MSI-H colorectal tumors, we looked for mutations in 25 coding repeats contained in eight genes...

Topics

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Base Pair Mismatch
Biomarkers, Tumor
Colorectal Neoplasms
Disease Progression
DNA Repair
Evolution, Molecular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Repetitive Sequences, Nucleic Acid

Tumor Cells, Cultured

Source

Identifiers

PMID: 11181575
DOI: 10.1093/hmg/10.5.513

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RAD50

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-11181575-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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