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Article

Distinct clinicopathologic and genetic profiles in sporadic gastric cancer with different mutator phenotypes.

Genes, chromosomes & cancer - 1 Apr 2000

Wu M S, Lee C W, Shun C T, Wang H P, Lee W J, Chang M C, Sheu J C, Lin J T

Abstract excerpt

A subset of sporadic gastric cancers (GC) exhibits microsatellite instability (MSI). To define the precise role of MSI in GC, a total of 100 patients with sporadic GC were classified into three groups, i.e., high-frequency MSI (MSI-H), low-frequency MSI (MSI-L), and microsatellite stable (MSS), based on 10 microsatellite markers. Mutational analyses of TGFbetaRII, IGFIIR, BAX, MSH3, MSH6, E2F4, MSH2, MLH1, and...

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Topics

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Share to Adaptor Proteins, Signal Transducing
Share to Genes, p53

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to MutL Protein Homolog 1

Share to MutS Homolog 2 Protein

Share to Neoplasm Proteins

Share to Polymorphism, Single-Stranded Conformational

Share to Proto-Oncogene Proteins

Share to Stomach Neoplasms

Source

Identifiers

PMID: 10719371

Genes

MLH1
BAX
MSH2
MSH3
MSH6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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