Article
Systematic identification of genes with coding microsatellites mutated in DNA mismatch repair-deficient cancer cells.
International journal of cancer - 1 Jul 2001
Woerner S M, Gebert J, Yuan Y P, Sutter C, Ridder R, Bork P, von Knebel Doeberitz M
Abstract excerpt
Microsatellite instability (MSI) caused by deficient DNA mismatch-repair functions is a hallmark of cancers associated with the hereditary nonpolyposis colorectal cancer (HNPCC) syndrome but is also found in about 15% of all sporadic tumors. Most affected microsatellites reside in untranslated intergenic or intronic sequences. However, recently few genes with coding microsatellites were also shown to be...
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