Article
Th1 and Th2 polymorphisms in Sjögren's syndrome and rheumatoid arthritis.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Jul 2014
de Souza Thayse Rodrigues, de Albuquerque Tavares Carvalho Alessandra, Duarte Ângela Pinto, Porter Stephen R, Leão Jair C, Gueiros Luiz Alcino
Abstract excerpt
BACKGROUND: Sjogren's syndrome is characterized by T-cell infiltration of exocrine glands leading to parenchymal destruction and impaired glandular function. This process is orchestrated by cytokines, whose secretion can be regulated by genetic polymorphisms. MATERIALS AND METHODS: The aim of this study was to investigate the influence of interleukin-6 -174G/C, interleukin-10 -1082G/A, tumor necrosis factor-α...
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