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Article

High expression of interleukine-1 receptor antagonist in rheumatoid arthritis: Association with IL1RN*2/2 genotype.

Autoimmunity - 1 Dec 2017

Ramírez-Pérez S, De la Cruz-Mosso U, Hernández-Bello J, Martínez-Bonilla G E, Ramírez-Dueñas M G, Pereira-Suárez A L, Parra Rojas I, Martínez-López E, Macías-Barragán J, Muñoz-Valle J F

Abstract excerpt

Rheumatoid arthritis (RA) is an autoimmune disease characterized by inflammation and pro-inflammatory cytokines production. IL-1Ra is an anti-inflammatory cytokine codified by IL1RN gene that blocks IL-1 signalling. A VNTR polymorphism of 86 bp in IL1RN gene has been associated with RA risk and regulation of IL-1Ra expression. In this study, we determined mRNA and protein expression of IL-1Ra in RA patients and...

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PMID: 29226727
DOI: 10.1080/08916934.2017.1412431

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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