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Article

Simian virus 40 T antigen-induced gonadotroph adenomas: a model of human null cell adenomas.

Endocrinology - 1 Jul 1998

Kumar T R, Graham K E, Asa S L, Low M J

Abstract excerpt

The cell of origin of human null cell pituitary adenomas is disputed. Although these tumors, by definition, do not produce any of the anterior pituitary hormones in vivo, they have been shown to express gonadotropin subunit genes, release gonadotropin hormones in vitro, and express the gonadotrop...

Topics

Adenoma
Animals
Antigens, Polyomavirus Transforming
Castration
Disease Models, Animal
Female
Follicle Stimulating Hormone
Immunohistochemistry
Luteinizing Hormone
Male
Mice
Mice, Transgenic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microscopy, Electron

Mutation

Pituitary Gland, Anterior

Pituitary Neoplasms

Source

Identifiers

PMID: 9645710
DOI: 10.1210/endo.139.7.6100

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9645710-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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