The gonadotroph origin of null cell adenomas.

doi:10.14310/horm.2002.1652

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Article

The gonadotroph origin of null cell adenomas.

Hormones (Athens, Greece) - 1 Apr 2016

Kontogeorgos George, Thodou Eleni

Abstract excerpt

OBJECTIVE: The term "null cell" adenoma was first proposed in 1980 to designate pituitary adenomas lacking clinical, biochemical and morphological markers to disclose their cell origin. DESIGN: The aim of this study was to investigate the presence of α- and β-gonadotropin subunits in clinically nonfunctioning pituitary tumors, which were initially immunonegative and thus diagnosed as null cell adenomas. For this...

Topics

Adenoma
Biomarkers, Tumor
Cell Lineage
Follicle Stimulating Hormone, beta Subunit
Glycoprotein Hormones, alpha Subunit
Humans
Immunohistochemistry
Luteinizing Hormone, beta Subunit
Microscopy, Electron
Phenotype
Pituitary Neoplasms
Terminology as Topic

Source

Open in PubMed

Identifiers

PMID: 27376427
DOI: 10.14310/horm.2002.1652

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