Article
Pituitary adenoma pathogenesis: an update.
Current opinion in endocrinology, diabetes, and obesity - 1 Aug 2012
Rostad Steve
Abstract excerpt
PURPOSE OF REVIEW: To describe the recent efforts to understand the molecular and genetic mechanisms involved in the tumorigenesis of pituitary adenomas. RECENT FINDINGS: There is rapidly accumulating evidence for the roles of molecular abnormalities in pituitary adenoma tumorigenesis, including dysregulation of the cell cycle, signal transduction pathways, oncogenes and tumor suppressor genes. MicroRNAs have...
Topics
- Adenoma
- Cell Cycle
- Cell Transformation, Neoplastic
- Female
- Genes, Tumor Suppressor
- Genetic Predisposition to Disease
- Humans
- Intercellular Signaling Peptides and Proteins
- Male
- Oncogenes
- Pituitary Neoplasms
- Signal Transduction
