Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immortalization of neuro-endocrine cells from adrenal tumors arising in SV40 T-transgenic mice.

Oncogene - 26 Jun 1997

Cairns L A, Crotta S, Minuzzo M, Ricciardi-Castagnoli P, Pozzi L, Ottolenghi S

Abstract excerpt

Pheochromocytomas are adrenal medullary tumors which arise from the transformation of neural crest-derived cells. In the course of studies of mice transgenic for an SV40 T-gene ectopically expressed in the adrenal medulla, we observed the occurrence of large, mainly bilateral tumors in a high proportion of transgenic animals. From these tumors we established immortalized cell lines which grow in vitro at 32...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Northern
Share to Cell Division
Share to Cytokines

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to Gene Expression Regulation, Neoplastic

Share to Mice, Transgenic

Share to Mutation

Source

Identifiers

PMID: 9223673
DOI: 10.1038/sj.onc.1201137

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immortalization of neuro-endocrine cells from adrenal tumors arising in SV40 T-transgenic mice.PMID 9223673Read ↗

Immortalization of pituitary cells at discrete stages of development by directed oncogenesis in transgenic miceSemantic proximity Read ↗

Adrenal-specific transgene expression and derivation of conditionally immortal rat adrenocortical cell lines.Semantic proximity Read ↗

Characterization of endocrine cell lines immortalized by a temperature-sensitive mutant SV40.Semantic proximity Read ↗

Pituitary tumour-transforming gene (PTTG) and pituitary senescence.Semantic proximity Read ↗

Establishment of tsA58 transgenic rats as a source of conditionally immortalized cell lines with differentiated functions.Semantic proximity Read ↗

Simian virus 40 T antigen-induced gonadotroph adenomas: a model of human null cell adenomas.Semantic proximity Read ↗

Generation and analysis of normal and shiverer temperature-sensitive immortalized cell lines exhibiting phenotypic characteristics of oligodendrocytes at several stages of differentiation.Semantic proximity Read ↗

Vascular smooth muscle cells of H-2Kb-tsA58 transgenic mice. Characterization of cell lines with distinct properties.Semantic proximity Read ↗

Phenotypes of human epithelial cell lines immortalized from benign mastopathies.Semantic proximity Read ↗

An immortalized mouse neuroepithelial cell line with neuronal and glial phenotypes.Semantic proximity Read ↗

Molecular phenotype of simian virus 40 large T antigen-induced primitive neuroectodermal tumors in four different lines of transgenic mice.Semantic proximity Read ↗

Growth properties of neural cell lines immortalized with the tsA58 allele of SV40 large T antigen.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.