Article
[The characteristics of the functional activity of the brain serotoninergic system in the manifestation of natural and pathological anxiety in mice: the effect of the genotype].
Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova - 1 Jan 2000
Avgustinovich D F, Lipina T V, Alekseenko O V, Amstislavskaia T G, Kudriatseva N N
Abstract excerpt
Anxiety was estimated in intact male mice of C57BL/6J (C57) and (CBA) and CBA/Lac (CBA) strains and in males of both strains after the repeated experience of social defeats (losers) in 10 daily aggressive confrontations. A plus-maze test for behavior in a novel situation and a partition test for communicative activity were applied. Tryptophan hydroxylase (TPH) activity, 5-hydroxytryptamine (5-HT) and...
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